Tablets containing açaí (Euterpe spp.) dried extract for dietary supplementation: A study of functional properties




drying technology, direct compression, cyanidin-3-rutinoside, LC-MS, spray drying, mechanical property


Açaí is a very popular functional food in the Amazon due to its nutritional properties, its high caloric value, and its high content of anthocyanins and phenolic compounds, which mainly confers antioxidant and anti-inflammatory activities. Thus, this study aimed at the development of immediate-release tablets containing açaí dried extract by direct compression. The extract was subjected to physical evaluation of the powder, quantification of total polyphenol (TP) content (mg EAG/g), total anthocyanin content (mg C3G/100 g), cyanidin-3-rutinoside marker (µg C3R/g) by LC-MS, obtention of the tablet, and their physical-mechanical evaluation. Açaí dried extract showed spherical shape particles, with smooth and rough surfaces and heterogeneous sizes, which are characteristic of dried powders when obtained by spray drying. In addition, the extract presented TP content (23.307± 2.190 mg EAG/g), total anthocyanins (10.52 mg C3G/100 g), and cyanidin-3-rutinoside (42 µg C3R/g). Tablets had good mechanical properties, good thermal stability under 200°C, and 3.65 µg C3R/g of cyanidin-3-rutinoside content per tablet unit. The results obtained in this study showed the possibility of obtaining tablets containing açaí dried extract with good mechanical properties and antioxidant activity aiming its use as a dietary supplement.


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Agência Nacional de Vigilância Sanitária (ANVISA) (2018). Resolução da Diretoria Colegiada - RDC nº 243, de 26 de julho de 2018. Dispõe sobre os requisitos sanitários dos suplementos alimentares. Diário Oficial da União, (144).

Aliakbarian, B., Casazza, A. A., & Perego, P. (2011). Valorization of olive oil solid waste using high pressure-high temperature reactor. Food Chemistry, 128(3), 704-710.

Borges, G. D. S. C., Vieira, F. G. K., Copetti, C., Gonzaga, L. V., & Fett, R. (2011). Optimization of the extraction of flavanols and anthocyanins from the fruit pulp of Euterpe edulis using the response surface methodology. Food Research International, 44(3), 708-715.

Carvalho, A. V., Ferreira Ferreira da Silveira, T., Mattietto, R. de A., Padilha de Oliveira, M. do S., & Godoy, H. T. (2017). Chemical composition and antioxidant capacity of açaí (Euterpe oleracea) genotypes and commercial pulps. Journal of the Science of Food and Agriculture, 97(5), 1467-1474.

Chandrasekhar, J., Madhusudhan, M. C., & Raghavarao, K. S. M. S. (2012). Extraction of anthocyanins from red cabbage and purification using adsorption. Food and Bioproducts Processing, 90(4), 615-623.

Cianchino, V. A., Favier, L. S., Ortega, C. A., Peralta, C., & Cifuente, D. A. (2020). Formulation development and evaluation of Silybum marianum tablets. Rodriguésia, 71.

Costa, R. G., Andreola, K., de Andrade Mattietto, R., de Faria, L. J. G. & Taranto, O. P. (2015). Effect of operating conditions on the yield and quality of açai (Euterpe oleracea Mart.) powder produced in spouted bed. LWT - Food Science and Technology, 64(2), 1196-1203.

da Silva Carvalho, A. G., da Costa Machado, M. T., da Silva, V. M., Sartoratto, A., Rodrigues, R. A. F., & Hubinger, M. D. (2016). Physical properties and morphology of spray dried microparticles containing anthocyanins of jussara (Euterpe edulis Martius) extract. Powder Technology, 294, 421-428.

da Silveira, T. F. F., Cristianini, M., Kuhnle, G. G., Ribeiro, A. B., Filho, J. T., & Godoy, H. T. (2019). Anthocyanins, non-anthocyanin phenolics, tocopherols and antioxidant capacity of açaí juice (Euterpe oleracea) as affected by high pressure processing and thermal pasteurization. Innovative Food Science and Emerging Technologies, 55, 88-96.

Fang, Z., & Bhandari, B. (2011). Effect of spray drying and storage on the stability of bayberry polyphenols. Food Chemistry, 129(3), 1139-1147.

Fernandes, R. V. de B., Botrel, D. A., Silva, E. K., Borges, S. V., Oliveira, C. R. de, Yoshida, M. I., Feitosa, J. P. de A., & de Paula, R. C. M. (2016). Cashew gum and inulin: New alternative for ginger essential oil microencapsulation. Carbohydrate Polymers, 153, 133-142.

Franceschinis, L., Salvatori, D. M., Sosa, N., & Schebor, C. (2014). Physical and Functional Properties of Blackberry Freeze- and Spray-Dried Powders. Drying Technology, 32(2), 197-207.

Ghribi, A. M., Gafsi, I. M., Blecker, C., Danthine, S., Attia, H., & Besbes, S. (2015). Effect of drying methods on physico-chemical and functional properties of chickpea protein concentrates. Journal of Food Engineering, 165, 179-188.

Giusti, M. M., & Wrolstad, R. E. (2001). Characterization and Measurement of Anthocyanins by UV-Visible Spectroscopy. Current Protocols in Food Analytical Chemistry.

Laokuldilok, T., & Kanha, N. (2015). Effects of processing conditions on powder properties of black glutinous rice (Oryza sativa L.) bran anthocyanins produced by spray drying and freeze drying. LWT - Food Science and Technology, 64(1), 405-411.

Loureiro Contente, D. M., Pereira, R. R., Rodrigues, A. M. C., da Silva, E. O., Ribeiro-Costa, R. M., & Carrera Silva-Júnior, J. O. (2020). Nanoemulsions of Acai Oil: Physicochemical Characterization for the Topical Delivery of Antifungal Drugs. Chemical Engineering and Technology, 43(7), 1424-1432.

Magalhães, T. S. S. de A., Macedo, P. C. de O., Converti, A., & de Lima, Á. A. N. (2020). The use of euterpe oleracea mart. As a new perspective for disease treatment and prevention. Biomolecules, 10(6), 813.

Nascimento, R. J. S. do, Couri, S., Antoniassi, R., & Freitas, S. P. (2008). Composição em ácidos graxos do óleo da polpa de açaí extraído com enzimas e com hexano. Revista Brasileira de Fruticultura, 30(2), 498-502.

Osorio, C., Forero, D. P., & Carriazo, J. G. (2011). Characterisation and performance assessment of guava (Psidium guajava L.) microencapsulates obtained by spray-drying. Food Research International, 44(5), 1174-1181.

Paim, D. R. S. F., Costa, S. D. O., Walter, E. H. M., & Tonon, R. v. (2016). Microencapsulation of probiotic jussara (Euterpe edulis M.) juice by spray drying. LWT, 74, 21-25.

Park, S., Valan Arasu, M., Lee, M. K., Chun, J. H., Seo, J. M., Lee, S. W., Al-Dhabi, N. A., & Kim, S. J. (2014). Quantification of glucosinolates, anthocyanins, free amino acids, and vitamin C in inbred lines of cabbage (Brassica oleracea L.). Food Chemistry, 145, 77-85.

Paul, S., & Sun, C. C. (2018). Systematic evaluation of common lubricants for optimal use in tablet formulation. European Journal of Pharmaceutical Sciences, 117, 118-127.

Rufino, M. do S. M., Alves, R. E., de Brito, E. S., Pérez-Jiménez, J., Saura-Calixto, F., & Mancini-Filho, J. (2010). Bioactive compounds and antioxidant capacities of 18 non-traditional tropical fruits from Brazil. Food Chemistry, 121(4), 996-1002.

Santamarina, A. B., Jamar, G., Mennitti, L. V., Ribeiro, D. A., Cardoso, C. M., Vera De Rosso, V., Oyama, L. M., Pisani, L. P., & Maione, F. (2019). Polyphenols-Rich Fruit (Euterpe edulis Mart.) Prevents Peripheral Inflammatory Pathway Activation by the Short-Term High-Fat Diet. Molecules, 24(9), 1655.

Schulz, M., Tischer Seraglio, S. K., Gonzaga, L. V., Costa, A. C. O., & Fett, R. (2021). Phenolic Compounds in Euterpe Fruits: Composition, Digestibility, and Stability–A Review. Food Reviews International, 39(1), 369-396.

Silva da Costa, R., Pinheiro, W. B. de S., Arruda, M. S. P., Costa, C. E. F., Converti, A., Ribeiro Costa, R. M., & Silva Júnior, J. O. C. (2022). Thermoanalytical and phytochemical study of the cupuassu (Theobroma grandiflorum Schum.) seed by-product in different processing stages. Journal of Thermal Analysis and Calorimetry, 147(1), 275-284.

Simon-Brown, K., Solval, K. M., Chotiko, A., Alfaro, L., Reyes, V., Liu, C., Dzandu, B., Kyereh, E., Goldson Barnaby, A., Thompson, I., Xu, Z., & Sathivel, S. (2016). Microencapsulation of ginger (Zingiber officinale) extract by spray drying technology. LWT - Food Science and Technology, 70, 119-125.

Tonon, R. v., Brabet, C., & Hubinger, M. D. (2008). Influence of process conditions on the physicochemical properties of açai (Euterpe oleraceae Mart.) powder produced by spray drying. Journal of Food Engineering, 88(3), 411-418.

Tonon, R. v., Brabet, C., & Hubinger, M. D. (2010). Anthocyanin stability and antioxidant activity of spray-dried açai (Euterpe oleracea Mart.) juice produced with different carrier agents. Food Research International, 43(3), 907-914.

Tonon, R. v., Brabet, C., Pallet, D., Brat, P., & Hubinger, M. D. (2009). Physicochemical and morphological characterisation of açai (Euterpe oleraceae Mart.) powder produced with different carrier agents. International Journal of Food Science and Technology, 44(10), 1950-1958.

Valente, M. da C. da C., do Nascimento, R. A., Santana, E. B., Ribeiro, N. F. da P., Costa, C. M. L., & de Faria, L. J. G. (2019). Spray drying of extract from Euterpe oleracea Mart.: Optimization of process and characterization of the açaí powder. Journal of Food Process Engineering, 42(8), e13253.

Yamaguchi, K. K. D. L., Pereira, L. F. R., Lamarão, C. V., Lima, E. S., & da Veiga-Junior, V. F. (2015). Amazon acai: Chemistry and biological activities: A review. Food Chemistry, 179, 137-151.




Como Citar

ARELLANO, L. F., DA COSTA, R. S., CONCEIÇÃO, E. C. da, RIBEIRO-COSTA, R. M., & SILVA JUNIOR, J. O. C. (2024). Tablets containing açaí (Euterpe spp.) dried extract for dietary supplementation: A study of functional properties. Food Science and Technology, 44.



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